ISSETUPDRIVEN

You have an .exe file that contains an .msi but when you extract that .msi from the .exe and attempt to run it you get the following error:

You can only run the installer from the Installer.exe

1. Create a transform with the following value located in the Properties table: ISSETUPDRIVEN = 1
2. Apply that transform the the msi and it should run

Note: This dosen't always work